KD-Validated Anti-MSI1 Mouse Monoclonal Antibody
Mouse monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB |
|---|---|
| Primary Accession | O43347 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Mouse IgG2a |
| Clone Names | 24GB13220 |
| Calculated MW | Predicted, 39 kDa, observed, 36 kDa |
| Gene Name | MSI1 |
| Aliases | MSI1; Musashi RNA Binding Protein 1; RNA-Binding Protein Musashi Homolog 1; Musashi-1; Musashi (Drosophila) Homolog 1; Musashi Homolog 1 (Drosophila); Musashi1 |
| Immunogen | Recombinant protein of human MSI1 |
| Gene ID | 4440 |
|---|---|
| Other Names | RNA-binding protein Musashi homolog 1, Musashi-1, MSI1 |
| Name | MSI1 |
|---|---|
| Function | RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU- 3' and other sequences containing the pattern 5'-[GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity). |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q61474}. Nucleus {ECO:0000250|UniProtKB:Q61474} |
| Tissue Location | Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines |

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